ANATOMOPATHOLOGICAL FEATURES OF HYPERTENSIVE PATIENTS OF A HEALTH PUBLIC UNITY OF RIBEIRÃO PRETO-SP

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Ana Paula Zambuzi Cardoso anafarma_usp@yahoo.com.br (1), Carolina Pinto Vieira (1), Daniel Valente Neves (1), Maria Alice Rossato Ferro (2), José Eduardo Velludo (3), Luiz de Souza (4), Miyeko Hayashida (5), Maria Suely Nogueira (5), Evandro José Cesarino (1).

(1) Faculdade de Ciências Farmacêuticas de Ribeirão Preto - FCFRP-USP, (2) SICAEV-SMS-RP, (3) IML-SPTC-SSP-SP, (4) Faculdade de Medicina de Ribeirão Preto - FMRP-USP, (5) Escola de Enfermagem de Ribeirão Preto - EERP-USP.

The mortality analysis by hypertensive diseases (HD) from 1991 to 2002 in Brazil (BR), state of São Paulo (SSP) and city of Ribeirão Preto (RP) identified that the proportional mortality and the mortality coefficient by HD in RP was greater than those of SSP and BR during all the studied period. The objective of this work was to analyze the anatomopathological features of hipertensive patients of a health public unity of RP. The casuistic was formed by a sample of adult individuals, from 20 years old, of both sexes, excluding pregnants with HD, into the 1601 patients seen during 1999 in the Ambulatory of Cardiology and Arterial Hypertension of CSE-FMRP-USP. 155 patients (9,68%) end up dead, of which 41 (26, 45%) were submitted to necropsy, being 25 (61%) men. Their age varied between 33 and 90 years old ( X=68,41 ± 0,08); 30 (73,1%) were white, with height from 1,41 to 1,78m (X= 1,60± 0,08), weight between 30 and 117 Kg (X= 66,9± 15,92); brain weight from 1070 to 1520g (X= 12,75±10,37); heart weight from 240 to 850g (X= 513,25±150,53); kidney weight from 40 to 300g (X=139,35± 54,72). The main causa mortis was acute myocardial infarction in 11 patients (26,8%). With exception of HD, the main disease was systemic atherosclerosis in 9 (21,95%). The main finding in the heart was coronary atherosclerosis in 27 (65,85%), followed by left ventricle concentric hypertrophy in 22 (53,65%). In the brain, the main finding was brain edema in 14 (34,14%). The ischemic brain vascular accident only happened in 7 (17,07%). In the kidneys, benign nephrosclerosis was found in 16 (39,02%). In the circulatory system, the most frequent finding was moderated systemic atherosclerosis in 20 (48,78%). In other organs, the main finding was chronic passive congestion of liver in 22 (53,65%). We concluded that the coronary atherosclerosis and systemic atherosclerosis were, possibly, the main determinants of the death of hypertensive people in RP, based on findings of necropsy, being that brain vascular accident did not happen in a significant number of cases.