Climacteric physically active women ingesting their routine diet oxidize more carbohydrates than lipids

NU03

Santos, RDS; Suen, VMM; Iannetta, O; Marchini, JS.

Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto (FMRP/USP).

Background: The brazilian female population who enter the climacteric is increasing, justified by the increase in women´s life expectation, and it is known that the proportion of obese is also increasing in Brazil, called nutritional transition. The largest proportion of obese may be explained in part by a possible drop in the substrates energy oxidation rate in this population. However, this possible drop is questionable by some studies, and in particular, there is a lack of knowledge in overweight climacteric women. Thus, the goal of this work was to study the influence of a brazilian routine diet in the substrates energy oxitation in climacteric women. Methods: Regularly attended patients were recruited from the Climacteric Clinic of Clinical Hospital of Ribeirão Preto (HCFMRP/USP). The patients were aged between 39 to 65 years, excluding those suffering from diabetes mellitus, hypertension, use of hormone replacement therapy, hypo-or hyperthyroidism. Anthropometric measurements, food frequency and physical activity questionnaires and indirect calorimetry were made. Results: According to the food questionnaire, the predominant diet was characterized by a mixed diet with lipids above the recommended levels. The carbohydrate oxidation rate after a 12 hours fasting was higher than the lipids (0.11±0.067 and 0.070±0.0176 grams per minute, respectively, p=0.014). The carbohydrate oxitation rate per kilogram of body weight showed significant positive correlation with the resting energy expenditure (p=0.001), carbohydrate intake in grams (p = 0.008), and negative with the lipid oxidation (p=0.001). The fat oxidation rate per kilogram of body weight showed significant negative correlation with body mass index (p=0.001), waist circumference (p=0.005) and the total daily caloric intake (p=0.03). Conclusion: A high carbohydrate intake and oxidation rate can contribute to weight gain in climacteric, as the reduced lipid oxidation rate as found in the present study. Key words: climacteric, substrate oxidation, indirect calorimetry. (Funding: FAPESP).